Novel mechanisms in alcohol neurodevelopmental disorders via BRCA1 depletion and BRCA1-dependent NADPH oxidase regulation

The breast cancer 1 protein (BRCA1) facilitates DNA repair, preventing embryolethality and protecting the fetus from reactive oxygen species (ROS)-induced developmental disorders mediated by oxidatively damaged DNA. Alcohol (ethanol, EtOH) exposure during pregnancy causes fetal alcohol spectrum diso...

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Detalles Bibliográficos
Autores principales: Drake, Danielle M., Wells, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577473/
https://www.ncbi.nlm.nih.gov/pubmed/34736119
http://dx.doi.org/10.1016/j.redox.2021.102148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577473/
https://www.ncbi.nlm.nih.gov/pubmed/34736119
http://dx.doi.org/10.1016/j.redox.2021.102148

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