A Novel Quality-Control Procedure to Improve the Accuracy of Rare Variant Calling in SNP Arrays

Background: Single-nucleotide polymorphism (SNP) arrays are an ideal technology for genotyping genetic variants in mass screening. However, using SNP arrays to detect rare variants [with a minor allele frequency (MAF) of <1%] is still a challenge because of noise signals and batch effects. An app...

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Detalles Bibliográficos
Autores principales: Sun, Ting-Hsuan, Shao, Yu-Hsuan Joni, Mao, Chien-Lin, Hung, Miao-Neng, Lo, Yi-Yun, Ko, Tai-Ming, Hsiao, Tzu-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577504/
https://www.ncbi.nlm.nih.gov/pubmed/34764980
http://dx.doi.org/10.3389/fgene.2021.736390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577504/
https://www.ncbi.nlm.nih.gov/pubmed/34764980
http://dx.doi.org/10.3389/fgene.2021.736390

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