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Evaluation of tumor mutational burden in small early hepatocellular carcinoma and progressed hepatocellular carcinoma

While researchers know that tumor mutational burden (TMB) is low in hepatocellular carcinoma (HCC), prior studies have not investigated TMB in cirrhosis, small early HCC and progressed HCC. HCC (n = 18) and cirrhosis (n = 6) cases were identified. TMB was determined by a 1.7 megabase, 409-gene next-...

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Detalles Bibliográficos
Autores principales: Wong, Mary, Kim, Jong T, Cox, Brian, Larson, Brent K, Kim, Stacey, Waters, Kevin M, Vail, Eric, Guindi, Maha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577511/
https://www.ncbi.nlm.nih.gov/pubmed/34765106
http://dx.doi.org/10.2217/hep-2020-0034