Cargando…

Glioblastoma cytotoxicity conferred through dual disruption of endolysosomal homeostasis by Vacquinol-1

BACKGROUND: Increased membrane trafficking is observed in numerous cancer types, including glioblastoma. Targeting the oncogenic driven acquired alterations in membrane trafficking by synthetic cationic amphiphilic small molecules has recently been shown to induce death of glioblastoma cells, althou...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwak, Dongoh, Hammarström, Lars G J, Haraldsson, Martin, Ernfors, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577523/
https://www.ncbi.nlm.nih.gov/pubmed/34765974
http://dx.doi.org/10.1093/noajnl/vdab152