Cross-Reactivity to Mutated Viral Immune Targets Can Influence CD8(+) T Cell Functionality: An Alternative Viral Adaptation Strategy

Loss of T cell immunogenicity due to mutations in virally encoded epitopes is a well-described adaptation strategy to limit host anti-viral immunity. Another described, but less understood, adaptation strategy involves the selection of mutations within epitopes that retain immune recognition, sugges...

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Detalles Bibliográficos
Autores principales: Currenti, Jennifer, Law, Becker M.P., Qin, Kai, John, Mina, Pilkinton, Mark A., Bansal, Anju, Leary, Shay, Ram, Ramesh, Chopra, Abha, Gangula, Rama, Yue, Ling, Warren, Christian, Barnett, Louise, Alves, Eric, McDonnell, Wyatt J., Sooda, Anuradha, Heath, Sonya L., Mallal, Simon, Goepfert, Paul, Kalams, Spyros A., Gaudieri, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577586/
https://www.ncbi.nlm.nih.gov/pubmed/34764960
http://dx.doi.org/10.3389/fimmu.2021.746986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577586/
https://www.ncbi.nlm.nih.gov/pubmed/34764960
http://dx.doi.org/10.3389/fimmu.2021.746986

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