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Disparities in Tumor Mutational Burden, Immunotherapy Use, and Outcomes Based on Genomic Ancestry in Non–Small-Cell Lung Cancer

PURPOSE: In patients with advanced non–small-cell lung cancer (aNSCLC), tumor mutational burden (TMB) may vary by genomic ancestry; however, its impact on treatment outcomes is unclear. This retrospective, observational study describes treatment patterns of patients with aNSCLC by genomic ancestry a...

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Detalles Bibliográficos
Autores principales: Brawley, Otis W., Luhn, Patricia, Reese-White, Deonna, Ogbu, Uzor C., Madhavan, Sriraman, Wilson, Gerren, Cox, Meghan, Ewing, Altovise, Hammer, Christian, Richie, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577674/
https://www.ncbi.nlm.nih.gov/pubmed/34752134
http://dx.doi.org/10.1200/GO.21.00309