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CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation

MHC-I associated peptides (MAPs) play a central role in the elimination of virus-infected and neoplastic cells by CD8 T cells. However, accurately predicting the MAP repertoire remains difficult, because only a fraction of the transcriptome generates MAPs. In this study, we investigated whether codo...

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Detalles Bibliográficos
Autores principales: Daouda, Tariq, Dumont-Lagacé, Maude, Feghaly, Albert, Benslimane, Yahya, Panes, Rébecca, Courcelles, Mathieu, Benhammadi, Mohamed, Harrington, Lea, Thibault, Pierre, Major, François, Bengio, Yoshua, Gagnon, Étienne, Lemieux, Sébastien, Perreault, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577786/
https://www.ncbi.nlm.nih.gov/pubmed/34679099
http://dx.doi.org/10.1371/journal.pcbi.1009482