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CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
MHC-I associated peptides (MAPs) play a central role in the elimination of virus-infected and neoplastic cells by CD8 T cells. However, accurately predicting the MAP repertoire remains difficult, because only a fraction of the transcriptome generates MAPs. In this study, we investigated whether codo...
Autores principales: | Daouda, Tariq, Dumont-Lagacé, Maude, Feghaly, Albert, Benslimane, Yahya, Panes, Rébecca, Courcelles, Mathieu, Benhammadi, Mohamed, Harrington, Lea, Thibault, Pierre, Major, François, Bengio, Yoshua, Gagnon, Étienne, Lemieux, Sébastien, Perreault, Claude |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577786/ https://www.ncbi.nlm.nih.gov/pubmed/34679099 http://dx.doi.org/10.1371/journal.pcbi.1009482 |
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