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Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis
Homozygous nonsense mutations in CEP55 are associated with several congenital malformations that lead to perinatal lethality suggesting that it plays a critical role in regulation of embryonic development. CEP55 has previously been studied as a crucial regulator of cytokinesis, predominantly in tran...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577787/ https://www.ncbi.nlm.nih.gov/pubmed/34710087 http://dx.doi.org/10.1371/journal.pgen.1009334 |