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Matrix metalloproteinase-1 expression is regulated by HIF-1-dependent and epigenetic mechanisms and serves a tumor-suppressive role in gastric cancer progression

The matrix metalloproteinase (MMP) family is associated with degradation of the extracellular matrix and is known to promote cancer invasion. The present study aimed to investigate the biological role of MMP-1 in gastric cancer cells and analyze the association between MMP-1 expression and the clini...

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Detalles Bibliográficos
Autores principales: Ito, Kotaro, Kitajima, Yoshihiko, Kai, Keita, Matsufuji, Shohei, Yamada, Kohei, Egawa, Noriyuki, Kitagawa, Hiroshi, Okuyama, Keiichiro, Tanaka, Tomokazu, Noshiro, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577796/
https://www.ncbi.nlm.nih.gov/pubmed/34738626
http://dx.doi.org/10.3892/ijo.2021.5282