Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas

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Ductal cells have been proposed as a source of adult β cell neogenesis, but this has remained controversial. By combining lineage tracing, 3D imaging, and single-cell RNA sequencing (scRNA-seq) approaches, we show that ductal cells contribute to the β cell population over time. Lineage tracing using...

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Detalles Bibliográficos
Autores principales: Gribben, Christopher, Lambert, Christopher, Messal, Hendrik A., Hubber, Ella-Louise, Rackham, Chloe, Evans, Ian, Heimberg, Harry, Jones, Peter, Sancho, Rocio, Behrens, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577827/
https://www.ncbi.nlm.nih.gov/pubmed/34478642
http://dx.doi.org/10.1016/j.stem.2021.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577827/
https://www.ncbi.nlm.nih.gov/pubmed/34478642
http://dx.doi.org/10.1016/j.stem.2021.08.003

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