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Visualization of individual cell division history in complex tissues using iCOUNT

The division potential of individual stem cells and the molecular consequences of successive rounds of proliferation remain largely unknown. Here, we developed an inducible cell division counter (iCOUNT) that reports cell division events in human and mouse tissues in vitro and in vivo. Analyzing cel...

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Detalles Bibliográficos
Autores principales: Denoth-Lippuner, Annina, Jaeger, Baptiste N., Liang, Tong, Royall, Lars N., Chie, Stefanie E., Buthey, Kilian, Machado, Diana, Korobeynyk, Vladislav I., Kruse, Merit, Munz, Clara M., Gerbaulet, Alexander, Simons, Benjamin D., Jessberger, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577829/
https://www.ncbi.nlm.nih.gov/pubmed/34525348
http://dx.doi.org/10.1016/j.stem.2021.08.012