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Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a

Although tumor-infiltrating regulatory T (Treg) cells play a pivotal role in tumor immunity, how Treg cell activation are regulated in tumor microenvironments remains unclear. Here, we found that mice deficient in the inhibitory immunoreceptor CD300a on their dendritic cells (DCs) have increased num...

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Detalles Bibliográficos
Autores principales: Nakazawa, Yuta, Nishiyama, Nanako, Koizumi, Hitoshi, Kanemaru, Kazumasa, Nakahashi-Oda, Chigusa, Shibuya, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577836/
https://www.ncbi.nlm.nih.gov/pubmed/34751648
http://dx.doi.org/10.7554/eLife.61999