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Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing

Keratinocytes, the predominant cell type of the epidermis, migrate to reinstate the epithelial barrier during wound healing. Mechanical cues are known to regulate keratinocyte re-epithelialization and wound healing; however, the underlying molecular transducers and biophysical mechanisms remain elus...

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Detalles Bibliográficos
Autores principales: Holt, Jesse R, Zeng, Wei-Zheng, Evans, Elizabeth L, Woo, Seung-Hyun, Ma, Shang, Abuwarda, Hamid, Loud, Meaghan, Patapoutian, Ardem, Pathak, Medha M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577841/
https://www.ncbi.nlm.nih.gov/pubmed/34569935
http://dx.doi.org/10.7554/eLife.65415