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Hypermethylation of DLG3 Promoter Upregulates RAC1 and Activates the PI3K/AKT Signaling Pathway to Promote Breast Cancer Progression

OBJECTIVE: This investigation aimed to figure out the relation between discs large homolog 3 (DLG3) expression and the progression and prognosis of breast cancer (BC). METHODS: qRT-PCR was utilized for confirming DLG3 expression and RAC1 mRNA expression in BC tissues and cells. Subsequently, after o...

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Detalles Bibliográficos
Autores principales: Liu, Bingbing, Xu, Yanning, Zhang, Lin, Yang, Xue, Chen, Ling, Liu, Yixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577895/
https://www.ncbi.nlm.nih.gov/pubmed/34765009
http://dx.doi.org/10.1155/2021/8428130