Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Attenuate Oxygen-Glucose Deprivation/Reperfusion-Induced Microglial Pyroptosis by Promoting FOXO3a-Dependent Mitophagy

BACKGROUND: Mesenchymal stem cell-derived exosomes (MSC-exos) have been recognized as a promising therapeutic strategy for neonatal hypoxic-ischemic brain damage (HIBD). Recently, microglial pyroptosis was shown to play a vital role in the progression of neonatal HIBD. However, whether MSC-exos impr...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Zhenzhen, Yuan, Ya, Zhang, Xiuli, Lu, Yifeng, Dong, Na, Jiang, Xiuqin, Xu, Jinjin, Zheng, Datong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577931/
https://www.ncbi.nlm.nih.gov/pubmed/34765084
http://dx.doi.org/10.1155/2021/6219715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577931/
https://www.ncbi.nlm.nih.gov/pubmed/34765084
http://dx.doi.org/10.1155/2021/6219715

Ejemplares similares