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Protectin DX promotes the inflammatory resolution via activating COX-2/L-PGDS-PGD(2) and DP(1) receptor in acute respiratory distress syndrome

PURPOSE: Acute respiratory distress syndrome (ARDS) is characterized by uncontrollable inflammation. Cyclooxygenase-2(COX-2) and its metabolite prostaglandins are known to promote the inflammatory resolution of ARDS. Recently, a newly discovered endogenous lipid mediator, Protectin DX (PDX), was als...

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Detalles Bibliográficos
Autores principales: Hu, Xin, Zhang, Ye-An, Chen, Ben, Jin, Zi, Lin, Mei-Lin, Li, Ming, Mei, Hong-Xia, Lu, Jia-Chao, Gong, Yu-Qiang, Jin, Sheng-Wei, Zheng, Sheng-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578004/
https://www.ncbi.nlm.nih.gov/pubmed/34920958
http://dx.doi.org/10.1016/j.intimp.2021.108348