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Positron Emission Tomographic Imaging of Tumor Cell Death Using Zirconium-89-Labeled APOMAB® Following Cisplatin Chemotherapy in Lung and Ovarian Cancer Xenograft Models

PURPOSE: Early detection of tumor treatment responses represents an unmet clinical need with no approved noninvasive methods. DAB4, or its chimeric derivative, chDAB4 (APOMAB®) is an antibody that targets the Lupus associated antigen (La/SSB). La/SSB is over-expressed in malignancy and selectively t...

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Detalles Bibliográficos
Autores principales: Liapis, Vasilios, Tieu, William, Wittwer, Nicole L., Gargett, Tessa, Evdokiou, Andreas, Takhar, Prab, Rudd, Stacey E., Donnelly, Paul S., Brown, Michael P., Staudacher, Alexander H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578059/
https://www.ncbi.nlm.nih.gov/pubmed/34231102
http://dx.doi.org/10.1007/s11307-021-01620-1