Network analysis reveals rare disease signatures across multiple levels of biological organization

Rare genetic diseases are typically caused by a single gene defect. Despite this clear causal relationship between genotype and phenotype, identifying the pathobiological mechanisms at various levels of biological organization remains a practical and conceptual challenge. Here, we introduce a networ...

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Detalles Bibliográficos
Autores principales: Buphamalai, Pisanu, Kokotovic, Tomislav, Nagy, Vanja, Menche, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578255/
https://www.ncbi.nlm.nih.gov/pubmed/34753928
http://dx.doi.org/10.1038/s41467-021-26674-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578255/
https://www.ncbi.nlm.nih.gov/pubmed/34753928
http://dx.doi.org/10.1038/s41467-021-26674-1

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