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An open-source automated PEG precipitation assay to measure the relative solubility of proteins with low material requirement

The solubility of proteins correlates with a variety of their properties, including function, production yield, pharmacokinetics, and formulation at high concentrations. High solubility is therefore a key requirement for the development of protein-based reagents for applications in life sciences, bi...

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Detalles Bibliográficos
Autores principales: Oeller, Marc, Sormanni, Pietro, Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578320/
https://www.ncbi.nlm.nih.gov/pubmed/34753962
http://dx.doi.org/10.1038/s41598-021-01126-4