Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma

Optic neuropathies such as glaucoma are characterized by retinal ganglion cell (RGC) degeneration and death. The sigma-1 receptor (S1R) is an attractive target for treating optic neuropathies as it is highly expressed in RGCs, and its absence causes retinal degeneration. Activation of the S1R exerts...

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Detalles Bibliográficos
Autores principales: Geva, Michal, Gershoni-Emek, Noga, Naia, Luana, Ly, Philip, Mota, Sandra, Rego, Ana Cristina, Hayden, Michael R., Levin, Leonard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578336/
https://www.ncbi.nlm.nih.gov/pubmed/34753986
http://dx.doi.org/10.1038/s41598-021-01077-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578336/
https://www.ncbi.nlm.nih.gov/pubmed/34753986
http://dx.doi.org/10.1038/s41598-021-01077-w

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