Cargando…

Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma

Optic neuropathies such as glaucoma are characterized by retinal ganglion cell (RGC) degeneration and death. The sigma-1 receptor (S1R) is an attractive target for treating optic neuropathies as it is highly expressed in RGCs, and its absence causes retinal degeneration. Activation of the S1R exerts...

Descripción completa

Detalles Bibliográficos
Autores principales: Geva, Michal, Gershoni-Emek, Noga, Naia, Luana, Ly, Philip, Mota, Sandra, Rego, Ana Cristina, Hayden, Michael R., Levin, Leonard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578336/
https://www.ncbi.nlm.nih.gov/pubmed/34753986
http://dx.doi.org/10.1038/s41598-021-01077-w