Local, multimodal intralesional therapy renders distant brain metastases susceptible to PD-L1 blockade in a preclinical model of triple-negative breast cancer

Despite recent progress in therapeutic strategies, prognosis of metastatic triple-negative breast cancer (TNBC) remains dismal. Evidence suggests that the induction and activation of tumor-residing conventional type-1 dendritic cells (cDC1s) is critical for the generation of CD8(+) T cells that medi...

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Detalles Bibliográficos
Autores principales: Yokoi, Toshihiro, Oba, Takaaki, Kajihara, Ryutaro, Abrams, Scott I., Ito, Fumito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578367/
https://www.ncbi.nlm.nih.gov/pubmed/34754037
http://dx.doi.org/10.1038/s41598-021-01455-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578367/
https://www.ncbi.nlm.nih.gov/pubmed/34754037
http://dx.doi.org/10.1038/s41598-021-01455-4

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