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PRMT3 promotes tumorigenesis by methylating and stabilizing HIF1α in colorectal cancer

Abnormal angiogenesis occurs during the growth of solid tumors resulting in increased vascular permeability to fluids and metastatic cancer cells. Anti-angiogenesis therapy for solid tumors is effective in the treatment of cancer patients. However, the efficacy of anti-angiogenesis therapy is limite...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Wang, Kexin, Feng, Xingbo, Wang, Jian, Chu, Yali, Jia, Chunmeng, He, Qingsi, Chen, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578369/
https://www.ncbi.nlm.nih.gov/pubmed/34753906
http://dx.doi.org/10.1038/s41419-021-04352-w