Cargando…

PRMT3 promotes tumorigenesis by methylating and stabilizing HIF1α in colorectal cancer

Abnormal angiogenesis occurs during the growth of solid tumors resulting in increased vascular permeability to fluids and metastatic cancer cells. Anti-angiogenesis therapy for solid tumors is effective in the treatment of cancer patients. However, the efficacy of anti-angiogenesis therapy is limite...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xin, Wang, Kexin, Feng, Xingbo, Wang, Jian, Chu, Yali, Jia, Chunmeng, He, Qingsi, Chen, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578369/ https://www.ncbi.nlm.nih.gov/pubmed/34753906 http://dx.doi.org/10.1038/s41419-021-04352-w

Ejemplares similares

PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis
por: Li, Zhongwei, et al.
Publicado: (2021)

MiRNA-543 promotes osteosarcoma cell proliferation and glycolysis by partially suppressing PRMT9 and stabilizing HIF-1α protein
por: Zhang, Heng, et al.
Publicado: (2016)

OLA1 promotes colorectal cancer tumorigenesis by activation of HIF1α/CA9 axis
por: Liu, Yue, et al.
Publicado: (2022)

PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis
por: Yin, Shasha, et al.
Publicado: (2021)

Regulation of HIF-1α stability by lysine methylation
por: Baek, Sung Hee, et al.
Publicado: (2016)

PRMT5 promotes colorectal cancer growth by interaction with MCM7
por: Li, Xiangwei, et al.
Publicado: (2021)

PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression
por: Li, Zhongwei, et al.
Publicado: (2023)

PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer
por: Yin, Xin-Ke, et al.
Publicado: (2021)

PRMT5-dependent p53 escape in tumorigenesis
por: Li, Yan, et al.
Publicado: (2015)

Implications of HIF-1α in the tumorigenesis and progression of pancreatic cancer
por: Jin, Xiao, et al.
Publicado: (2020)

PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6
por: Jia, Yachun, et al.
Publicado: (2023)

Protection of c-Fos from autophagic degradation by PRMT1-mediated methylation fosters gastric tumorigenesis
por: Kim, Eunji, et al.
Publicado: (2023)

PRMT5 facilitates angiogenesis and EMT via HIF-1α/VEGFR/Akt signaling axis in lung cancer
por: Zheng, Yonghua, et al.
Publicado: (2023)

PRMT5 activates AKT via methylation to promote tumor metastasis
por: Huang, Lei, et al.
Publicado: (2022)

TIPE1 inhibits osteosarcoma tumorigenesis and progression by regulating PRMT1 mediated STAT3 arginine methylation
por: Yang, Minghao, et al.
Publicado: (2022)

USP7- and PRMT5-dependent G3BP2 stabilization drives de novo lipogenesis and tumorigenesis of HNSC
por: Wang, Nan, et al.
Publicado: (2023)

The PRMT6/PARP1/CRL4B Complex Regulates the Circadian Clock and Promotes Breast Tumorigenesis
por: Yang, Tianshu, et al.
Publicado: (2023)

Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis
por: Liu, Xian-De, et al.
Publicado: (2014)

Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis
por: Kim, Yunho, et al.
Publicado: (2016)

LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1
por: Sun, Yang, et al.
Publicado: (2022)

PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP
por: Deng, Xiaolan, et al.
Publicado: (2015)

HIF-1α signaling: Essential roles in tumorigenesis and implications in targeted therapies
por: Zhao, Yan, et al.
Publicado: (2023)

Methylation of HBP1 by PRMT1 promotes tumor progression by regulating actin cytoskeleton remodeling
por: Wang, Jiyin, et al.
Publicado: (2022)

PRMT3 drives glioblastoma progression by enhancing HIF1A and glycolytic metabolism
por: Liao, Yunfei, et al.
Publicado: (2022)

PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer
por: Hartley, Antja-Voy, et al.
Publicado: (2020)

HIF1α stabilization in hypoxia is not oxidant-initiated
por: Kumar, Amit, et al.
Publicado: (2021)

Glycogen synthase kinase GSK3α promotes tumorigenesis by activating HIF1/VEGFA signaling pathway in NSCLC tumor
por: Cao, Xiaonian, et al.
Publicado: (2022)

In vivo functional dissection of a context-dependent role for Hif1α in pancreatic tumorigenesis
por: Cheng, T, et al.
Publicado: (2016)

HIF-1α promotes kidney organoid vascularization and applications in disease modeling
por: Peng, Kexin, et al.
Publicado: (2023)

Regulation of a PRMT5/NF-κB Axis by Phosphorylation of PRMT5 at Serine 15 in Colorectal Cancer
por: Hartley, Antja-Voy, et al.
Publicado: (2020)

SUMOylated MAFB promotes colorectal cancer tumorigenesis
por: Yang, Lin-Sen, et al.
Publicado: (2016)

DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer
por: Hou, Pingfu, et al.
Publicado: (2019)

CHD1 deletion stabilizes HIF1α to promote angiogenesis and glycolysis in prostate cancer
por: Wang, Yu-Zhao, et al.
Publicado: (2023)

The role of the HIF‐1α/ALYREF/PKM2 axis in glycolysis and tumorigenesis of bladder cancer
por: Wang, Jing‐Zi, et al.
Publicado: (2021)

Arginine methylation of Piwi proteins, catalyzed by dPRMT5, is required for Ago3 and Aub stability
por: Kirino, Yohei, et al.
Publicado: (2009)

TiPARP forms nuclear condensates to degrade HIF-1α and suppress tumorigenesis
por: Zhang, Lu, et al.
Publicado: (2020)

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model
por: Vanderborght, Bart, et al.
Publicado: (2020)

PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1
por: Xie, Fei, et al.
Publicado: (2023)

PRMT1 methylates METTL14 to modulate its oncogenic function
por: Wang, Jingchao, et al.
Publicado: (2023)

Stabilization of HIF-1α alleviates osteoarthritis via enhancing mitophagy
por: Hu, Sunli, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hngu7t0kv65au674l716oq9mh3