CD73-positive extracellular vesicles promote glioblastoma immunosuppression by inhibiting T-cell clonal expansion

Extracellular vesicles are involved in the occurrence, progression and metastasis of glioblastoma (GBM). GBM can secrete a variety of tumour-derived extracellular vesicles (TDEVs) with high immunosuppressive activity that remotely suppress the systemic immune system, and therapy targeting TDEVs has...

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Detalles Bibliográficos
Autores principales: Wang, Ming, Jia, Jiaoying, Cui, Yan, Peng, Yong, Jiang, Yugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578373/
https://www.ncbi.nlm.nih.gov/pubmed/34753903
http://dx.doi.org/10.1038/s41419-021-04359-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578373/
https://www.ncbi.nlm.nih.gov/pubmed/34753903
http://dx.doi.org/10.1038/s41419-021-04359-3

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