Single-molecule imaging with cell-derived nanovesicles reveals early binding dynamics at a cyclic nucleotide-gated ion channel

Ligand binding to membrane proteins is critical for many biological signaling processes. However, individual binding events are rarely directly observed, and their asynchronous dynamics are occluded in ensemble-averaged measures. For membrane proteins, single-molecule approaches that resolve these d...

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Detalles Bibliográficos
Autores principales: Patel, Vishal R., Salinas, Arturo M., Qi, Darong, Gupta, Shipra, Sidote, David J., Goldschen-Ohm, Marcel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578382/
https://www.ncbi.nlm.nih.gov/pubmed/34753946
http://dx.doi.org/10.1038/s41467-021-26816-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578382/
https://www.ncbi.nlm.nih.gov/pubmed/34753946
http://dx.doi.org/10.1038/s41467-021-26816-5

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