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Mouse strain-specific polymorphic provirus functions as cis-regulatory element leading to epigenomic and transcriptomic variations

Polymorphic integrations of endogenous retroviruses (ERVs) have been previously detected in mouse and human genomes. While most are inert, a subset can influence the activity of the host genes. However, the molecular mechanism underlying how such elements affect the epigenome and transcriptome and t...

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Detalles Bibliográficos
Autores principales: Zhou, Xuemeng, Sam, Tsz Wing, Lee, Ah Young, Leung, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578388/
https://www.ncbi.nlm.nih.gov/pubmed/34753915
http://dx.doi.org/10.1038/s41467-021-26630-z