Cargando…

Hsp90 chaperone code and the tumor suppressor VHL cooperatively regulate the mitotic checkpoint

Heat shock protein-90 (Hsp90) is an essential molecular chaperone in eukaryotes that plays a vital role in protecting and maintaining the functional integrity of deregulated signaling proteins in tumors. We have previously reported that the stability and activity of the mitotic checkpoint kinase Mps...

Descripción completa

Detalles Bibliográficos
Autores principales: Woodford, Mark R., Backe, Sarah J., Wengert, Laura A., Dunn, Diana M., Bourboulia, Dimitra, Mollapour, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578495/
https://www.ncbi.nlm.nih.gov/pubmed/34586601
http://dx.doi.org/10.1007/s12192-021-01240-2