3-D vascularized breast cancer model to study the role of osteoblast in formation of a pre-metastatic niche

Breast cancer cells (BCCs) preferentially metastasize to bone. It is known that BCCs remotely primes the distant bone site prior to metastasis. However, the reciprocal influence of bone cells on the primary tumor is relatively overlooked. Here, to study the bone-tumor paracrine influence, a tri-cell...

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Detalles Bibliográficos
Autores principales: Rimal, Rahul, Desai, Prachi, Marquez, Andrea Bonnin, Sieg, Karina, Marquardt, Yvonne, Singh, Smriti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578551/
https://www.ncbi.nlm.nih.gov/pubmed/34754042
http://dx.doi.org/10.1038/s41598-021-01513-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578551/
https://www.ncbi.nlm.nih.gov/pubmed/34754042
http://dx.doi.org/10.1038/s41598-021-01513-x

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