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A site of vulnerability at V3 crown defined by HIV-1 bNAb M4008_N1
Identification of vulnerable sites defined by broadly neutralizing antibodies (bNAbs) on HIV-1 envelope (Env) is crucial for vaccine design, and we present here a vulnerable site defined by bNAb M4008_N1, which neutralizes about 40% of a tier-2 virus panel. A 3.2 Å resolution cryo-EM structure of M4...
Autores principales: | Chan, Kun-Wei, Luo, Christina C., Lu, Hong, Wu, Xueling, Kong, Xiang-Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578649/ https://www.ncbi.nlm.nih.gov/pubmed/34753944 http://dx.doi.org/10.1038/s41467-021-26846-z |
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