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Vitamin K Epoxide Reductase Complex Subunit 1-Like 1 (VKORC1L1) Inhibition Induces a Proliferative and Pro-inflammatory Vascular Smooth Muscle Cell Phenotype

Background: Vitamin K antagonists (VKA) are known to promote adverse cardiovascular remodeling. Contrarily, vitamin K supplementation has been discussed to decelerate cardiovascular disease. The recently described VKOR-isoenzyme Vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) is invo...

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Detalles Bibliográficos
Autores principales: Aksoy, Adem, Al Zaidi, Muntadher, Repges, Elena, Becher, Marc Ulrich, Müller, Cornelius, Oldenburg, Johannes, Zimmer, Sebastian, Nickenig, Georg, Tiyerili, Vedat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578699/
https://www.ncbi.nlm.nih.gov/pubmed/34778390
http://dx.doi.org/10.3389/fcvm.2021.708946