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Repair or Degrade: the Thermodynamic Dilemma of Cellular Protein Quality-Control

Life is a non-equilibrium phenomenon. Owing to their high free energy content, the macromolecules of life tend to spontaneously react with ambient oxygen and water and turn into more stable inorganic molecules. A similar thermodynamic picture applies to the complex shapes of proteins: While a polype...

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Detalles Bibliográficos
Autores principales: Fauvet, Bruno, Rebeaud, Mathieu E., Tiwari, Satyam, De Los Rios, Paolo, Goloubinoff, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578701/
https://www.ncbi.nlm.nih.gov/pubmed/34778379
http://dx.doi.org/10.3389/fmolb.2021.768888