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Repair or Degrade: the Thermodynamic Dilemma of Cellular Protein Quality-Control
Life is a non-equilibrium phenomenon. Owing to their high free energy content, the macromolecules of life tend to spontaneously react with ambient oxygen and water and turn into more stable inorganic molecules. A similar thermodynamic picture applies to the complex shapes of proteins: While a polype...
Autores principales: | Fauvet, Bruno, Rebeaud, Mathieu E., Tiwari, Satyam, De Los Rios, Paolo, Goloubinoff, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578701/ https://www.ncbi.nlm.nih.gov/pubmed/34778379 http://dx.doi.org/10.3389/fmolb.2021.768888 |
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