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Activation of parabrachial nucleus - ventral tegmental area pathway underlies the comorbid depression in chronic neuropathic pain in mice

Depression symptoms are often found in patients suffering from chronic pain, a phenomenon that is yet to be understood mechanistically. Here, we systematically investigate the cellular mechanisms and circuits underlying the chronic-pain-induced depression behavior. We show that the development of ch...

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Detalles Bibliográficos
Autores principales: Zhang, Ludi, Wang, Jing, Niu, Chenxu, Zhang, Yu, Zhu, Tiantian, Huang, Dongyang, Ma, Jing, Sun, Hui, Gamper, Nikita, Du, Xiaona, Zhang, Hailin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578703/
https://www.ncbi.nlm.nih.gov/pubmed/34731609
http://dx.doi.org/10.1016/j.celrep.2021.109936