Cargando…

Quantal Ca(2+) release mediated by very few IP(3) receptors that rapidly inactivate allows graded responses to IP(3)

Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are intracellular Ca(2+) channels that link extracellular stimuli to Ca(2+) signals. Ca(2+) release from intracellular stores is “quantal”: low IP(3) concentrations rapidly release a fraction of the stores. Ca(2+) release then slows or terminates with...

Descripción completa

Detalles Bibliográficos
Autores principales: Rossi, Ana M., Riley, Andrew M., Dupont, Geneviève, Rahman, Taufiq, Potter, Barry V.L., Taylor, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578705/
https://www.ncbi.nlm.nih.gov/pubmed/34731613
http://dx.doi.org/10.1016/j.celrep.2021.109932