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Quantal Ca(2+) release mediated by very few IP(3) receptors that rapidly inactivate allows graded responses to IP(3)
Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are intracellular Ca(2+) channels that link extracellular stimuli to Ca(2+) signals. Ca(2+) release from intracellular stores is “quantal”: low IP(3) concentrations rapidly release a fraction of the stores. Ca(2+) release then slows or terminates with...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578705/ https://www.ncbi.nlm.nih.gov/pubmed/34731613 http://dx.doi.org/10.1016/j.celrep.2021.109932 |