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Impact of Antibiotics and Proton Pump Inhibitors on Efficacy and Tolerance of Anti-PD-1 Immune Checkpoint Inhibitors
BACKGROUND: The use of antibiotics (ATB) and proton-pump inhibitors (PPI) alters the composition and diversity of the gut microbiota, which can influence the immune system, consequently interfering with response to anti-PD1 immune checkpoint inhibitors (ICI). We assessed the impact of ATB and/or PPI...
Autores principales: | Giordan, Quentin, Salleron, Julia, Vallance, Catherine, Moriana, Clothilde, Clement-Duchene, Christelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578856/ https://www.ncbi.nlm.nih.gov/pubmed/34777340 http://dx.doi.org/10.3389/fimmu.2021.716317 |
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