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Ilicicolin A Exerts Antitumor Effect in Castration-Resistant Prostate Cancer Via Suppressing EZH2 Signaling Pathway

The Polycomb protein enhancer of zeste homolog 2 (EZH2) has critical roles in prostate cancer (PCa) progression and drug-resistance, which remains an obstacle for PCa treatment. Enzalutamide (ENZ) is a second-generation androgen receptor antagonist employed for treatment of metastatic castration-res...

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Detalles Bibliográficos
Autores principales: Guo, Lang, Luo, Xiaowei, Yang, Ping, Zhang, Yanting, Huang, Jialuo, Wang, Hong, Guo, Yinfeng, Huang, Weifeng, Chen, Zhiqiang, Wang, Shusheng, Wang, Junjian, Lei, Jinping, Xiang, Songtao, Liu, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578973/
https://www.ncbi.nlm.nih.gov/pubmed/34776951
http://dx.doi.org/10.3389/fphar.2021.723729