Angiogenesis is Inhibited by Arsenic Trioxide Through Downregulation of the CircHIPK3/miR-149-5p/FOXO1/VEGF Functional Module in Rheumatoid Arthritis

Angiogenesis is a crucial event in the pathogenesis of rheumatoid arthritis (RA). Arsenic trioxide (ATO, As(2)O(3)) has been reported to inhibit synovial angiogenesis via the vascular endothelial growth factor (VEGF)-centered functional module. However, the exact mechanisms of ATO on VEGF modulation...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Ma, Yeye, Zhang, Yue, Niu, Sijia, Chu, Maolin, Zhang, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579003/
https://www.ncbi.nlm.nih.gov/pubmed/34776969
http://dx.doi.org/10.3389/fphar.2021.751667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579003/
https://www.ncbi.nlm.nih.gov/pubmed/34776969
http://dx.doi.org/10.3389/fphar.2021.751667

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