Cargando…

Angiogenesis is Inhibited by Arsenic Trioxide Through Downregulation of the CircHIPK3/miR-149-5p/FOXO1/VEGF Functional Module in Rheumatoid Arthritis

Angiogenesis is a crucial event in the pathogenesis of rheumatoid arthritis (RA). Arsenic trioxide (ATO, As(2)O(3)) has been reported to inhibit synovial angiogenesis via the vascular endothelial growth factor (VEGF)-centered functional module. However, the exact mechanisms of ATO on VEGF modulation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Juan, Ma, Yeye, Zhang, Yue, Niu, Sijia, Chu, Maolin, Zhang, Zhiyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579003/ https://www.ncbi.nlm.nih.gov/pubmed/34776969 http://dx.doi.org/10.3389/fphar.2021.751667

Ejemplares similares

Circular RNA circHIPK3 is downregulated in diabetic cardiomyopathy and overexpression of circHIPK3 suppresses PTEN to protect cardiomyocytes from high glucose-induced cell apoptosis
por: Jiang, Jun, et al.
Publicado: (2022)

CircHIPK2 promotes proliferation of nasopharyngeal carcinoma by down-regulating HIPK2
por: Zhang, Dan, et al.
Publicado: (2022)

CircHIPK3 Plays Vital Roles in Cardiovascular Disease
por: Zhang, Lei, et al.
Publicado: (2021)

Biogenesis, cellular effects, and biomarker value of circHIPK3
por: Fu, Yihan, et al.
Publicado: (2021)

Circular RNA CircHIPK3 Promotes Gemcitabine Sensitivity in Bladder Cancer
por: Xie, Fang, et al.
Publicado: (2020)

Emerging landscape of circHIPK3 and its role in cancer and other diseases
por: Shao, Qi, et al.
Publicado: (2021)

Understanding the Dual Roles of CircHIPK3 in Tumorigenesis and Tumor Progression
por: Wei, Zeyu, et al.
Publicado: (2022)

Exosomal CircHIPK3 Released from Hypoxia-Induced Cardiomyocytes Regulates Cardiac Angiogenesis after Myocardial Infarction
por: Wang, Yan, et al.
Publicado: (2020)

Mechanism of RNA circHIPK3 Involved in Resistance of Lung Cancer Cells to Gefitinib
por: Zhao, Yi, et al.
Publicado: (2022)

Regulation of Podocyte Injury by CircHIPK3/FUS Complex in Diabetic Kidney Disease
por: Liu, Feng, et al.
Publicado: (2022)

CircHIPK3: Key Player in Pathophysiology and Potential Diagnostic and Therapeutic Tool
por: Zhou, Jiang, et al.
Publicado: (2021)

Down-regulation of circular RNA ITCH and circHIPK3 in gastric cancer tissues
por: GHASEMI, Sara, et al.
Publicado: (2018)

Circular RNA circ_HIPK3 is down-regulated and suppresses cell proliferation, migration and invasion in osteosarcoma
por: Xiao-Long, Ma, et al.
Publicado: (2018)

BMSC-Derived Exosomal CircHIPK3 Promotes Osteogenic Differentiation of MC3T3-E1 Cells via Mitophagy
por: Ma, Shaoyang, et al.
Publicado: (2023)

circHIPK3 regulates lung fibroblast-to-myofibroblast transition by functioning as a competing endogenous RNA
por: Zhang, Jia-xiang, et al.
Publicado: (2019)

circHIPK3 promotes oxaliplatin-resistance in colorectal cancer through autophagy by sponging miR-637
por: Zhang, Yanli, et al.
Publicado: (2019)

CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7
por: Zeng, Kaixuan, et al.
Publicado: (2018)

CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer
por: Wang, Chong, et al.
Publicado: (2023)

CircHIPK2 Contributes to DDP Resistance and Malignant Behaviors of DDP-Resistant Ovarian Cancer Cells Both in vitro and in vivo Through circHIPK2/miR-338-3p/CHTOP ceRNA Pathway
por: Cao, Yang, et al.
Publicado: (2021)

Sp1-Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7
por: Yan, Junyu, et al.
Publicado: (2021)

Stem cell-derived exosomes prevent pyroptosis and repair ischemic muscle injury through a novel exosome/circHIPK3/ FOXO3a pathway
por: Yan, Bing, et al.
Publicado: (2020)

circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA
por: Okholm, Trine Line Hauge, et al.
Publicado: (2023)

CircHIPK3 Promotes the Tumorigenesis and Development of Gastric Cancer Through miR-637/AKT1 Pathway
por: Yang, Dejun, et al.
Publicado: (2021)

circHIPK3 Exacerbates Folic Acid-Induced Renal Tubulointerstitial Fibrosis by Sponging miR-30a
por: Wu, Yan, et al.
Publicado: (2022)

circHIPK3 prevents cardiac senescence by acting as a scaffold to recruit ubiquitin ligase to degrade HuR
por: Ding, Fengzhi, et al.
Publicado: (2022)

Inhibition of angiogenesis by arsenic trioxide via TSP-1–TGF-β1-CTGF–VEGF functional module in rheumatoid arthritis
por: Zhang, Juan, et al.
Publicado: (2017)

Arsenic Trioxide Suppressed Migration and Angiogenesis by Targeting FOXO3a in Gastric Cancer Cells
por: Zhang, Lin, et al.
Publicado: (2018)

Prolactin-Responsive Circular RNA circHIPK3 Promotes Proliferation of Mammary Epithelial Cells from Dairy Cow
por: Liu, Jia, et al.
Publicado: (2020)

Serum Extracellular Vesicle-Derived circHIPK3 and circSMARCA5 Are Two Novel Diagnostic Biomarkers for Glioblastoma Multiforme
por: Stella, Michele, et al.
Publicado: (2021)

circHIPK3 (hsa_circ_0000284) Promotes Proliferation, Migration and Invasion of Breast Cancer Cells via miR-326
por: Qi, Liqiang, et al.
Publicado: (2021)

circHIPK3 Promotes Cell Proliferation and Migration of Gastric Cancer by Sponging miR-107 and Regulating BDNF Expression
por: Wei, Juan, et al.
Publicado: (2020)

CircHIPK3 promotes proliferation and metastasis and inhibits apoptosis of renal cancer cells by inhibiting MiR-485-3p
por: Lai, Jinjin, et al.
Publicado: (2020)

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs
por: Zheng, Qiupeng, et al.
Publicado: (2016)

Dysregulation of the miR‐30c/DLL4 axis by circHIPK3 is essential for KSHV lytic replication
por: Harper, Katherine L, et al.
Publicado: (2022)

CircHIPK3 overexpression accelerates the proliferation and invasion of prostate cancer cells through regulating miRNA-338-3p
por: Cai, Chengkuan, et al.
Publicado: (2019)

Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2
por: Zhang, Yuan, et al.
Publicado: (2019)

circHIPK2-mediated σ-1R promotes endoplasmic reticulum stress in human pulmonary fibroblasts exposed to silica
por: Cao, Zhouli, et al.
Publicado: (2017)

Circular RNA circHIPK3 Promotes Cell Metastasis through miR-637/STAT3 Axis in Osteosarcoma
por: Huang, Zhongyue, et al.
Publicado: (2020)

Therapeutic Potential of Exosomal circRNA Derived from Synovial Mesenchymal Cells via Targeting circEDIL3/miR-485-3p/PIAS3/STAT3/VEGF Functional Module in Rheumatoid Arthritis
por: Zhang, Juan, et al.
Publicado: (2021)

CircHIPK3 relieves vascular calcification via mediating SIRT1/PGC-1α/MFN2 pathway by interacting with FUS
por: Feng, Siyi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6r30n49ik20c7h9vrq6vf32geb