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Production and purification of high-titer OrfV for preclinical studies in vaccinology and cancer therapy

Poxviruses have been used extensively as vaccine vectors for human and veterinary medicine and have recently entered the clinical realm as immunotherapies for cancer. We present a comprehensive method for producing high-quality lots of the poxvirus Parapoxvirus ovis (OrfV) for use in preclinical mod...

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Detalles Bibliográficos
Autores principales: van Vloten, Jacob P., Minott, Jessica A., McAusland, Thomas M., Ingrao, Joelle C., Santry, Lisa A., McFadden, Grant, Petrik, James J., Bridle, Byram W., Wootton, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579082/
https://www.ncbi.nlm.nih.gov/pubmed/34786436
http://dx.doi.org/10.1016/j.omtm.2021.08.004