Cargando…
Generation of HLA Universal Megakaryocytes and Platelets by Genetic Engineering
Patelet transfusion refractoriness remains a relevant hurdle in the treatment of severe alloimmunized thrombocytopenic patients. Antibodies specific for the human leukocyte antigens (HLA) class I are considered the major immunological cause for PLT transfusion refractoriness. Due to the insufficient...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579098/ https://www.ncbi.nlm.nih.gov/pubmed/34777386 http://dx.doi.org/10.3389/fimmu.2021.768458 |