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Generation of HLA Universal Megakaryocytes and Platelets by Genetic Engineering

Patelet transfusion refractoriness remains a relevant hurdle in the treatment of severe alloimmunized thrombocytopenic patients. Antibodies specific for the human leukocyte antigens (HLA) class I are considered the major immunological cause for PLT transfusion refractoriness. Due to the insufficient...

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Detalles Bibliográficos
Autores principales:	Figueiredo, Constanca, Blasczyk, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579098/ https://www.ncbi.nlm.nih.gov/pubmed/34777386 http://dx.doi.org/10.3389/fimmu.2021.768458

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