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Gaining insights into relevance across cancers based on mutation features of TP53 gene
The tumor suppressor gene TP53, one of the most frequently mutated genes, is recognized as the guardian of genome and can provide a significant barrier to neoplastic transformation and tumor progression. Traditional theory believes that TP53 mutations are equal among cancer types. However, to date,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579115/ https://www.ncbi.nlm.nih.gov/pubmed/34786492 http://dx.doi.org/10.1016/j.bbrep.2021.101165 |