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Gaining insights into relevance across cancers based on mutation features of TP53 gene

The tumor suppressor gene TP53, one of the most frequently mutated genes, is recognized as the guardian of genome and can provide a significant barrier to neoplastic transformation and tumor progression. Traditional theory believes that TP53 mutations are equal among cancer types. However, to date,...

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Detalles Bibliográficos
Autores principales: Mei, Yue, Liang, Dong, Wang, Tengjiao, Yu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579115/
https://www.ncbi.nlm.nih.gov/pubmed/34786492
http://dx.doi.org/10.1016/j.bbrep.2021.101165