Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is characterized by ectopic accumulation of triglycerides in the liver. Emerging evidence has demonstrated that lipophagy regulates lipid mobilization and energy homeostasis in the liver. Sirtuin 3 (SIRT3), a mitochondrial NAD(+)-dependent deacet...

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Detalles Bibliográficos
Autores principales: Liu, Jingxin, Zhang, Tian, Zhu, Jianzhong, Ruan, Shuangchen, Li, Rongsong, Guo, Bing, Lin, Ligen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579168/
https://www.ncbi.nlm.nih.gov/pubmed/34758848
http://dx.doi.org/10.1186/s13020-021-00528-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579168/
https://www.ncbi.nlm.nih.gov/pubmed/34758848
http://dx.doi.org/10.1186/s13020-021-00528-w

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