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Mutational patterns and their correlation to CHIP-related mutations and age in hematological malignancies

Acquired somatic mutations are crucial for the development of most cancers. We performed a comprehensive comparative analysis of the mutational landscapes and their correlation with CHIP-related (clonal hematopoiesis of indeterminate potential) mutations and patient age of 122 genes in 3096 cases of...

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Detalles Bibliográficos
Autores principales: Stengel, Anna, Baer, Constance, Walter, Wencke, Meggendorfer, Manja, Kern, Wolfgang, Haferlach, Torsten, Haferlach, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579257/
https://www.ncbi.nlm.nih.gov/pubmed/34570179
http://dx.doi.org/10.1182/bloodadvances.2021004668