Clonal expansion of CD8(+) T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI

Donor lymphocyte infusion (DLI) is a standard of care for relapse of acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation. Currently it is poorly understood how and when CD8(+) αβ T cells exert graft-versus-leukemia (GVL) activity after DLI. Also, there is no reliable biom...

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Detalles Bibliográficos
Autores principales: Schultze-Florey, Christian R., Kuhlmann, Leonie, Raha, Solaiman, Barros-Martins, Joana, Odak, Ivan, Tan, Likai, Xiao, Yankai, Ravens, Sarina, Hambach, Lothar, Venturini, Letizia, Stadler, Michael, Eder, Matthias, Thol, Felicitas, Heuser, Michael, Förster, Reinhold, Ganser, Arnold, Prinz, Immo, Koenecke, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579265/
https://www.ncbi.nlm.nih.gov/pubmed/34535011
http://dx.doi.org/10.1182/bloodadvances.2020004073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579265/
https://www.ncbi.nlm.nih.gov/pubmed/34535011
http://dx.doi.org/10.1182/bloodadvances.2020004073

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