R4 RGS proteins suppress engraftment of human hematopoietic stem/progenitor cells by modulating SDF-1/CXCR4 signaling

Homing and engraftment of hematopoietic stem/progenitor cells (HSPCs) into the bone marrow (BM) microenvironment are tightly regulated by the chemokine stromal cell–derived factor-1 (SDF-1) and its G-protein–coupled receptor C-X-C motif chemokine receptor 4 (CXCR4), which on engagement with G-protei...

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Detalles Bibliográficos
Autores principales: Chan, Kathy Yuen Yee, Zhang, Chi, Wong, Yorky Tsin Sik, Zhang, Xiao-Bing, Wang, Chi Chiu, Ng, Wing Hei, Fok, Siu Ping, Tang, Patrick Ming Kuen, Kang, Wei, Feng, Bo, Poon, Ellen Ngar Yun, Lee, King Yiu, Lee, Cheuk Kwong, Chen, Chun, Leung, Tak Yeung, Ng, Margaret Heung Ling, To, Ka Fai, Wang, Han, Lam, Hugh Simon, Ng, Pak Cheung, Yuen, Patrick Man Pan, Li, Karen, Leung, Alex Wing Kwan, Li, Chi Kong, Leung, Kam Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579266/
https://www.ncbi.nlm.nih.gov/pubmed/34500454
http://dx.doi.org/10.1182/bloodadvances.2020003307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8579266/
https://www.ncbi.nlm.nih.gov/pubmed/34500454
http://dx.doi.org/10.1182/bloodadvances.2020003307

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